Contraindications
Hypersensitivity, renal and chronic heart failure.
Carefully
The drug should be used with caution in patients with impaired renal excretory function and hypokalemia.
Use during pregnancy and lactation
The use of the drug during pregnancy and lactation is possible only if the expected benefit to the mother outweighs the potential risk to the fetus (adequate and strictly controlled studies have not been conducted).
Purpose of the solution Disol for infusion
The drug contains cations and acetate. The last component has an alkalizing effect. Disol solution is prescribed to improve blood microcirculation and prevent disseminated intravascular coagulation syndrome.
The product not only has a detoxifying effect, it prevents the formation of blood clots in small vessels. Disol is a medicine intended for parenteral use. It is available in 200 and 400 ml packages. The drug is based on acetate and sodium chloride.
Application of Disol
You should know the indications for using the Disol dropper. It is prescribed to people who have been diagnosed with hypertensive dehydration. The drug restores strength in cases of shock resulting from severe intestinal diseases. Disol can be prescribed to a person with kidney failure. The drug removes poisons that enter the body as a result of alcohol intoxication.
Contraindications
Disol has contraindications. It is not recommended for people who have hypersensitivity to the main and auxiliary components. For a patient who has chronic heart or kidney disease, the doctor prescribes a safer analogue.
The use of Disol may cause electrolyte imbalance. Contraindication is vomiting, which leads to dehydration. The solution for infusion is not recommended for patients taking diuretic medications or corticosteroids. Disol is contraindicated for people who have a fever for a long time.
Use during pregnancy and lactation
Disol does not affect the fetus, but the drug is prescribed to pregnant women in extreme cases. Its active components pass into breast milk, so during the treatment period you need to stop lactation.
Doses, side symptoms
Disol is administered intravenously or by drip, the doctor warms it up before use. For patients with a decompensated condition, the solution is administered using the jet method. For moderate dehydration, the drug is administered by drip. Dosages are individual and depend on body weight.
The drug may cause side symptoms. If the patient is allergic to its components, swelling, shortness of breath, and chills occur. Uncontrolled use leads to impaired kidney and lung function. Disol is prescribed strictly according to indications; independent use is unacceptable. The medicine is stored at temperatures from 0 to + 24 degrees. A solution with sediment is not suitable for use.
Directions for use and doses
Intravenously (stream and drip), under the control of laboratory parameters. The ratio of the administered fluid and diuresis is determined every 6 hours. Within 1 hour, a solution is administered in an amount corresponding to 7-10% of the patient’s body weight; then the jet injection is replaced by a drip injection, for 24-48 hours, at a speed of 40-120 drops/min. Before administration, the solution is heated to 36-38 °C. The solution is administered in quantities necessary to restore the volume of fluid lost through feces, vomit, urine, and sweat.
In severe forms of diseases (hypovolemic infectious-toxic shock, decompensated metabolic acidosis, anuria), they begin with a jet administration of the drug, followed by a transition to a drip.
For milder forms of diseases (intoxication and dehydration, metabolic acidosis, oliguria), you can limit yourself to drip administration of the drug.
After eliminating hyperkalemia, further water-salt therapy is carried out with Trisol, Acesol or Chlosol solutions.
Nutriflex Omega Plus - analogue
This medicine is intended for parenteral nutrition. It contains fats and biologically active acids. Nutriflex Omega Plus restores water and electrolyte balance. The drug is prescribed to patients who need to compensate for the lack of proteins, fats and glucose.
Read more about the indications
Nutriflex Omega Plus prevents vitamin deficiency and also replenishes the lack of fluid. The drug is recommended for patients after complex surgery. Other indications: burns, injuries. The main indication for use is the inability to feed enterally.
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The medicine contains glucose, this substance provides energy and improves amino acid metabolism. The amino acids contained in the drug synthesize the protein necessary for the smooth functioning of the body.
Nutriflex Omega Plus contains lipids that prevent thrombophlebitis. If the doctor has prescribed a hypertensive drug, the risk of developing this pathology increases.
Active components, methods of use
Nutriflex Omega Plus, an analogue of Disol, contains glucose, oil, acetate, sodium chloride. Other active ingredients, including trace elements, strengthen blood vessels, increasing their elasticity. Citric acid and distilled water act as excipients.
The medicine is intended for intravenous administration. It is prescribed to patients who, for some reason, cannot receive enteral nutrition or if enteral nutrition is prohibited. Indication for use is catabolism.
Contraindications, adverse reactions
Nutriflex omega-plus is not prescribed to people who have allergies. Contraindications are increased amounts of lipids in the blood, renal failure, diseases that impair blood clotting. The doctor does not administer this drug for any shock conditions. A safer analogue is recommended for people with diabetes. Nutriflex Omega Plus is prohibited for pregnant and nursing mothers.
The drug is administered intravenously, the duration of the infusion is individual, depending on the weight, as well as the need for proteins and amino acids. An overdose is extremely rare, but it leads to shortness of breath, increased sweating, and a feeling of heat. Exceeding the dose is dangerous, as it may affect the functioning of the lungs.
The drug may cause side effects, including allergies, fever, and dermatological rash. Anaphylactic shock is rare. This condition requires urgent attention. In some patients, blood pressure increases and heart rhythm is disturbed. Medicine containing suspensions is unsuitable for use.
Trisol
Trisol is a medicinal solution that replenishes the lack of fluid. Just like Disol, it is prescribed to patients with electrolyte imbalance. The drug replaces plasma, restores electrolyte balance, reduces metabolic acidosis, and improves blood composition.
Effect on the body, active components, indications
Trisol has a diuretic effect. It removes poisons from the body that disrupt the functioning of internal organs. The drug restores blood circulation in the capillaries, normalizes heart rhythm, improves the functioning of the heart and kidneys. Trisol is available in bottles of different sizes: minimum - 100 ml, maximum - 500 ml.
The active substance of the serum is sodium chloride, the auxiliary component is distilled water. Trisol should not be used in parallel with medications containing potassium. The main indication for use is dehydration (loss of fluid) resulting from poisoning.
Trisol is recommended for patients who are allergic to other similar solutions. Indications for use are cholera and dysentery. The solution is intended for intravenous administration. Before use, the doctor warms it to the optimal temperature.
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According to indications, the drug can be administered in a stream, followed by a drip. If intoxication occurs, which leads to dehydration or oliguria, Trisol is administered by drip. Dehydration treatment lasts 2 hours. The dose of Trisol is individual, depending on weight.
In what situations is the solution not prescribed?
The doctor prescribes the dosage taking into account the volume of fluid lost. If the patient develops hyperkalemia, the drug must be changed. It is contraindicated in pregnant and breastfeeding women. Other contraindications: kidney failure, heart failure, excess potassium in the body, severe brain pathology.
If a patient is allergic to Trisol components, the doctor recommends a safer analogue. The drug may cause side effects: shortness of breath, vomiting, but such reactions are rare. It is recommended to store the drug in a dry place.
Introduction Features
Acesol is used in cases where drugs with a similar mechanism of action cannot be administered orally. This is usually typical for those diseases in which patients have severe vomiting, weakness, and loss of consciousness.
In the first hour, Acesol is recommended to be injected into a vein slowly. On average, 7-10% solution of body weight is required. Then they switch to drip administration. The rate of delivery of the medicine should be in the range from 40 to 120 drops per minute. Dehydration therapy is carried out for 1-2 days. The total amount of solution and the frequency of IV placement is determined by the severity of the patient’s condition and the data of blood and urine tests.
When using Acesol, a number of rules should be followed:
- Before infusion, the solution must be warmed to 36-38 degrees. Freezing the medicine is not a contraindication to its use, since after thawing the therapeutic properties of the components and their safety do not change.
- When administering the medication by drip, tests must be repeated every 6 hours. This will allow timely detection of hyperkalemia.
- During drip use of Acesol, you need to monitor your vital signs. The patient needs to periodically measure blood pressure and pulse, and evaluate the functioning of the cardiovascular system.
The dosage for a child is selected individually. Excessive amounts of solution can lead to edema and deterioration of heart function.
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Possible adverse reactions
Acesol is a salt preparation that does not cause harm when used correctly. However, you need to know that some people experience side effects that include:
- severe chills;
- tachycardia;
- the appearance of edema.
In most cases, all unwanted reactions occur due to rapid drip administration or incorrectly calculated dosage. Correction of the treatment regimen allows minimizing adverse reactions, so most often Acesol is not discontinued.
Hyperkalemia, an increase in the concentration of potassium in the blood, is considered a serious complication. Subjectively, hyperkalemia manifests itself as abnormal heart rhythm, muscle weakness, decreased amount of urine, vomiting, and convulsions. If such symptoms are recorded, the patient needs to have an ECG and tests for potassium levels. If an increase in the concentration of the microelement is confirmed, Acesol is discontinued and replaced with Disol. Lack of timely treatment for hyperkalemia can lead to respiratory paralysis and cardiac arrest.
Comparison of safety of Disol and Trisol
The safety of a drug includes many factors.
At the same time, it is higher for Disol than for Trisol. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Disol, as well as Trisol, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Disol has fewer risks when used than Trisol.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Disol and Trisol.