“Tavegil” injections: instructions for use, effectiveness, reviews

Tavegil injections are an antihistamine, one of the best in this area. It has been prescribed by doctors for many years to improve the quality of life of people suffering from allergies. But before using the injection solution, you should know how it works, what its specifics are, how it is used, and whether there are any contraindications.

According to the latest statistics, a large number of fatal diseases that occur in humans are the result of allergic reactions. It can all start with a slight itching in the nose or sneezing, runny nose, or red spots on the human body. Every year about 7 million people on the planet die from allergies. The extent of this disease's impact is significant. Almost all of us have an allergic enzyme in our bodies, and some don't even know it.

Compound

All forms of the medicine include the active ingredient clemastine in the form of clemastine hydrofumarate .
1 ml of solution contains 1 mg of active substance. Additional substances are: sodium citrate, ethanol, injection water, propylene glycol, sorbitol.

Tavegil tablets contain 1 mg of the active substance, as well as the following additional substances: povidone, lactose monohydrate, talc, magnesium stearate and corn starch.

Analogues of the drug

There are many antihistamines available now. They differ in price and features of action. "Tavegil" belongs to the first generation of such drugs, as well as "Suprastin", "Diazolin", "Pipolfen" and some other drugs. They are different because they have different composition. There are also medications that have the same active ingredient as Tavegil: Clemastine, Rivtagil, Bravegil. Only a doctor can decide which drug to choose for treatment.

Pharmacodynamics and pharmacokinetics

The main active ingredient in the drug Tavegil is clemastine . In addition to the antiallergic effect, it has an anticholinergic, sedative effect, and reduces the permeability of the vascular wall. The drug does not have a hypnotic effect. Tavegil prevents contraction of smooth muscles and the development of vasodilation caused by the action of histamine. Clemastine reduces itching, has a local anesthetic effect, inhibits the formation of edema, exudation , and reduces the permeability of the capillary wall. During the experiment, it was found that Tavegil does not have teratogenic, mutagenic, or carcinogenic effects . When taking dosages 300 times higher than normal, fertility . After oral administration, the maximum effect is recorded after 6 hours and lasts up to 12 hours. Converted to metabolites in the liver, which are excreted 45-65 percent in the urine. Also, a small part is displayed unchanged.

Compatibility with other drugs

Tavegil is from the group of antihistamines that can enhance the effects of other medications. It mainly increases the effects of sleeping pills and sedatives. If you take sleeping pills and sedatives together, you can cause an overdose, which will be accompanied by a lack of coordination and even loss of consciousness. Therefore, you cannot take such drugs together, and if this is unavoidable, you need to reduce the dose. But under no circumstances should you do this yourself without consulting a specialized doctor.

Tavegil is one of the drugs that have long been known to mankind in the treatment of allergies. Every day the market is filled with new products used in this area, but tavegil is still in demand. Characterized by minor contraindications. It is always worth remembering that only a doctor can prescribe it after taking tests based on an assessment of the patient’s health condition.

Indications for use of Tavegil

What are the tablets for, and what are the solution and syrup used for?

The medicine is prescribed for allergic urticaria , hay fever, allergic rhinitis, eczema, pruritic dermatosis , contact dermatitis, drug allergies , allergies to insect bites. Indications for the use of Tavegil are also: hemorrhagic vasculitis , serum sickness, pseudoallergic reaction, anaphylactic shock, acute iridocyclitis .

What is tavegil used for?

Tavegil injections are used in the treatment of many diseases, including allergies. The groups of diseases in the treatment of which this remedy is used include:

• allergic dermatosis;
• contact dermatitis;
• atopic dermatitis;
• reaction to insect bites;
• skin rash, redness after vaccinations, provoked by the consumption of allergens present in food or medicines;
• chronic eczema;
• acute eczema.

Tavegil also becomes a great help during hay fever and colds, as an additional drug to the main therapy. But the most common use of the drug is to eliminate allergy symptoms.

Nowadays, allergies are quite common among the population; almost every third citizen is exposed to this disease. And this drug is an excellent treatment for this. Tavegil in ampoules should be used only after consulting a doctor, since the drug has side effects, and self-medication is extremely dangerous.

Contraindications

Tavegil is contraindicated during pregnancy, intolerance to clemastine, and breastfeeding. The drug is not used in the treatment of MAO inhibitors, bronchial asthma, diseases of the lower respiratory tract, or in pediatrics. For pyloric stenosis , bladder neck obstruction, angle-closure glaucoma, prostatic hyperplasia, heart disease, thyrotoxicosis , arterial hypertension, Tavegil is used with caution. Children under one year of age are prescribed the drug in the form of injection solutions and syrup. The tablet form of the drug can be taken after reaching 6 years of age.

Features of application

Among the many antihistamines, Tavegil injections do not lose their popularity. The instructions for use note that this drug has few side effects. It does not affect the brain, so it generally does not cause drowsiness or inhibition of reactions. Only some patients complain that when treated with Tavegil they feel sleepy. Moreover, this is not drowsiness and lethargy, but simply a desire to fall asleep, while mental reactions remain normal. Sometimes there may also be trembling of the limbs. Therefore, it is not recommended to drive a car or operate other mechanisms that require concentration during treatment with the drug.

In addition, the instructions for the use of Tavegil injections note that it should be used with caution as part of complex treatment. It is advisable that the drug be prescribed by a doctor who understands the interactions of different drugs. For example, Tavegil can enhance the effect of antidepressants, antipsychotics, sleeping pills and sedatives. In this case, depression of the central nervous system is observed. It is prohibited to use this drug together with MAO blockers.

Side effects

Nervous system: tremors of the limbs, dizziness, increased drowsiness, fatigue, feeling tired, headaches, impaired coordination of movements, lethargy. In children, there is a stimulating effect of the drug on the nervous system, manifested by convulsions, euphoria , agitation, anxiety, neuritis , paresthesia , hysteria, and insomnia.

Sense organs: tinnitus, acute labyrinthitis , diplopia, disturbances in the functioning of the visual analyzer.

Digestive system: gastralgia , dyspeptic disorders, stool disorders, vomiting, loss of appetite, dry mouth.

Urinary system: difficulty urinating, frequent urge.

Respiratory system: nasal congestion, disturbances and difficulty breathing, pressure behind the sternum, difficulty in separating sputum, thickening of the secretion of the bronchial tree.

Cardiovascular system: extrasystole , rapid heartbeat, drop in blood pressure.

Hematopoietic organs: agranulocytosis, thrombocytopenia, hemolytic anemia . Possible development of bronchospasm , anaphylactic shock, shortness of breath, photosensitivity.

Consequences of overdose

If the drug is used incorrectly or administered in doses higher than recommended, an overdose occurs. Most often this happens in children for whom the amount of medication is incorrectly calculated. For them, this immediately affects the state of the nervous system: it is depressed or, conversely, excited. Children often develop insomnia, hysteria, nervousness and even seizures.

The consequences of an overdose may also include the following symptoms:

• tachycardia;
• flushes of blood to the face;
• enlarged pupils;
• dry mouth, thirst;
• nausea, abdominal pain;
• anemia;
• increased frequency of urination.

Instructions for use of Tavegil (Method and dosage)

Tavegil tablets, instructions for use

The tablet form is taken orally twice a day at a dosage of 1 mg. The maximum permissible daily amount of Tavegil is 6 mg. Children: 0.5 mg twice a day. For children from 1 to 6 years old, the medicine is prescribed in the form of syrup, 1 teaspoon. It is not recommended to use the drug for children under 1 year of age.

Instructions for use of Tavegil in ampoules

Intravenous and intramuscular administration of the drug is carried out twice a day, 2 mg; children from 1 year to 12 years are given injections of 12.5 mcg/kg 2 times. To prevent allergies, 2 mg of clemastine is administered slowly intravenously once. The contents of the ampoule must be dissolved in 0.9% NaCl.

The medicine is not produced in the form of an ointment.

Who should not use the drug

Not everyone can receive Tavegil injections, even in emergency cases. The instructions for use note that absolute contraindications include the following conditions:

• children under one year of age;
• lactation period;
• first trimester of pregnancy;
• presence of bronchial asthma during exacerbation;
• individual intolerance to the components of the drug.

In addition, sometimes the use of the drug is not strictly prohibited, but only not recommended. In these cases, Tavegil injections can be given, but only in special cases, for example, when there is a threat to life, and always under the supervision of a doctor. This is the second trimester of pregnancy, cardiovascular diseases, gastric ulcers, bladder stenosis, prostatitis, glaucoma. Only in serious life-threatening situations is the drug used in children under 6 years of age. In addition, the active substance of the drug is metabolized in the liver and excreted by the kidneys. Therefore, if the functioning of these organs is disrupted, it must be used with great caution.

special instructions

According to the annotation, the injection solution contains ethanol . During the treatment period, it is recommended to avoid drinking alcoholic beverages. Intra-arterial administration of the drug is not allowed. Elderly patients and children require careful monitoring during treatment. Tavegil is discontinued 72 hours before allergy tests in order to exclude the results of allergy prick tests . Tavegil affects driving vehicles and controlling complex mechanisms.

MNN: Clemastine.

Contraindications to the use of Tavegil

Like most drugs, the medication has its contraindications, which undoubtedly must be adhered to. Tavegil is contraindicated:

1. small children under one year old;
2. during an attack of bronchial asthma;
3. if the patient has allergic reactions to any of the components of the drug;

In addition to contraindications, the instructions for the drug also talk about conditions in which special care must be taken:

1. during the period of bearing a child;
2. if the patient suffers from a stomach ulcer, as well as a duodenal ulcer;
3. during bladder stenosis;
4. during gastric stenosis;
5. if there is an enlarged prostate;
6. with angle-closure glaucoma.

Tavegil can be safely called a first-generation drug that is used in the treatment of allergies. Of course, today there are a lot of modern medications that are used to treat this disease, but Tavegil injections still remain popular. They are time-tested, reliable and guaranteed to provide the desired result.

Overdose

The pharmaceutical drug tavegil in ampoules must be used strictly as directed by a specialized doctor. Increasing the dose of this medication on your own is very dangerous, since excessive use can cause an overdose of the pharmaceutical drug.

Overdose symptoms:

1. The nervous system is the first to suffer. According to statistics, stimulant effects occur mainly in children. A child's body undergoes this reaction much more often than an adult;
2. During an overdose, the pupils may also dilate significantly, dry mouth may be observed, and blood will rush to the head;
3. Pain in the gastrointestinal tract, nausea and vomiting are also common symptoms.

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What should you do during an overdose?

The first thing to do is to induce vomiting. A fairly important point in such a situation is gastric lavage, which can be done using a sodium chloride solution. You can also use a saline laxative. During all these procedures, current symptoms should be dealt with. Sedatives and painkillers will not interfere.

Analogues of Tavegil

Level 4 ATC code matches:
Benadryl

Clemastine

Sungmil

Donormil

Diphenhydramine

There are no direct analogues, but the drugs have a similar effect: Diphenhydramine , Suprastin , Pipolfen .

Tavegil price, where to buy

The price of Tavegil in 1 mg tablets is 120 rubles for 10 pieces, and 175 rubles for 20 pieces.

How much do allergy pills cost in Ukraine? The cost, for example, in Kharkov is 90 UAH for a package of 20 pieces.

The price of Tavegil in 2 ml ampoules is 185 rubles for 5 pieces.

It is extremely difficult to buy syrup in pharmacies.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Tavegil Tavegyl antiallergic drug, tablets, 1 mg, 20 pcs. Famar Italia SpA RUB
  221 order
• Tavegil Tavegyl antiallergic drug, tablets, 1 mg, 10 pcs. Famar Italy S.p.A.

  RUB 168 order

Pharmacy Dialogue

• Tavegil antiallergic drug, tablets 1 mg N20Famar Italia Spa

  230 rub. order

• Tavegil antiallergic drug, tablets 1 mg N10Famar Italia Spa

  84 rub. order

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Pharmacy24

• Tavegil 2 mg 2 ml No. 5 injection solution Takeda Austria GmbH, Austria
  97 UAH.order
• Tavegil 1 mg No. 20 tablets Famar Italy S.p.A. , Italy

  79 UAH order

PaniPharmacy

• Tavegil ampoule Tavegil solution d/in. 1mg/ml amp. 2ml No. 5 Austria, Takeda Austria

  104 UAH order

• Tavegil tablets Tavegil tablets. 1 mg No. 20 Italy, Famar Italia

  92 UAH order

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Mode of application

If it makes sense to use the drug, tavegil is administered intramuscularly or into a vein. The dose is calculated individually for each patient, it all depends on the characteristics and condition of the patient’s body. It is strictly forbidden to use the drug and set the dosage yourself. Thus, you can only worsen the condition.

The drug must be diluted in saline, regardless of the dosage. For a milliliter of the drug, 5 ml is used. saline solution.

Action of Tavegil in ampoules

As soon as the drug enters the body, it quickly spreads throughout it and gives the desired effect, as a result of which it stabilizes the person’s condition. Helps counteract the accumulation of mast cells and blocks M-cholinergic receptors. 10-20 minutes after administration, the effect is achieved and the patient’s condition improves.

1. there is a reduction in the percentage permeability of small capillaries in the vascular wall;
2. intercellular fluid is released;
3. The central nervous system of the body calms down.

The medication also has a sedative effect on the patient’s brain, as a result of which he does not feel drowsiness and inhibited reactions.

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Following the instructions, injections of the drug can be used by women breastfeeding. It contains clemastine, which is well absorbed in the intestinal walls within 2 hours. After clemastine enters the bloodstream, it has an excellent effect on plasma proteins, so it is not observed in milk. For pregnant women, the use of these injections is possible only after the appointment of a specialized doctor.

Most of the drug is eliminated from the human body through the kidneys; a small amount is excreted through the liver. Patients who have problems with these organs should not increase the dosage prescribed by the doctor.

Tavegil injections for pregnant women

The instructions say that during pregnancy it is best for expectant mothers to avoid this pharmaceutical product. But, in some situations, tavegil for allergies for pregnant women is the only salvation, and its use becomes simply inevitable.

Allergies are manifestations of a protective reaction of the human body in which damage to its own tissues occurs. According to statistics, approximately 20% of pregnant women suffer from allergies. Such indicators are very terrifying, but understandable. Nowadays, allergies can be varied, but they are divided into mild and severe forms.

It doesn’t matter what type of allergy a pregnant woman has, it must be treated. It is in such situations that Tavegil ampoules are used, but only after being prescribed by the attending physician. Tavegil brings positive results if it is used as prescribed by a specialized doctor.