Vaccination will protect children’s health from dangerous infectious and viral diseases.

Description of the drug

The Infanrix vaccine is the latest combined vaccine based on safe pertussis antigens, the first vaccine in Russia for the prevention of whooping cough, diphtheria and tetanus with an acellular pertussis component.

Infanrix is ​​used to prevent diseases characterized by severe course and possible death. The relevance and prevalence of these infections continues to this day, and the low incidence rate is ensured solely by creating an “immune layer” through vaccination from an early age.

Directions for use and doses

A single dose is 0.5 ml, contained in a specially designed syringe. This syringe dose of the Infanrix vaccine is aseptically packaged and adapted for convenient transportation and storage, equipped with a special needle that minimizes pain from the injection. The use of such a syringe eliminates overdose and reuse.

The Infanrix vaccine is administered intramuscularly into the thigh. Injection into the buttock is not currently practiced. Intravenous administration is strictly contraindicated.

Compatibility of Infanrix with other vaccines

The Infanrix vaccine can be administered simultaneously with all drugs from the national calendar of preventive vaccinations on the same day, in different parts of the body, with the exception of the BCG vaccine.

The use of the Infanrix vaccine in combination with other vaccinations does not affect their immunogenicity (ability to develop immunity). Tolerability of vaccines does not deteriorate, and the number of adverse reactions does not increase. It is allowed to mix the Infanrix vaccine with the Hiberix vaccine (vaccine against Haemophilus influenzae type b) in one syringe.

Administering several vaccines on the same day does not place an excessive burden on the immune system. Infanrix can be used to complete a course of vaccination started with other vaccines against whooping cough, diphtheria and tetanus, as well as for revaccination if necessary. All vaccines in the Russian national vaccination calendar are interchangeable.

Is it possible to have both vaccinations?

Before vaccination, it is important to decide what kind of immunoprophylaxis to use. Both vaccines cannot be used at the same time, since they contain antigens against whooping cough, tetanus and diphtheria: if two drugs are administered, there will be an overdose, the body may not be able to cope with such a load. Doctors recommend vaccination with Infanrix Hexa or regular Infanrix and vaccines against polio, hepatitis B and hemophilus influenzae infection. After Infanrix, revaccination of Hex is allowed.

Vaccination scheme

The course of primary vaccination consists of 3 doses of vaccine administered according to the National Calendar of Preventive Vaccinations of the Russian Federation at 3 - 4.5 - 6 months. In case of violation of the vaccination course schedule, the subsequent interval between the administration of the next dose of Infanrix® does not change and is 1.5 months. Revaccination is carried out 12 months after the third dose of the primary vaccination course.

In all cases of violation of the vaccination schedule, the doctor must be guided by the National Calendar of Preventive Vaccinations of the Russian Federation.

Side effects

The Infanrix vaccine has lower reactogenicity compared to whole cell vaccines (DTP). Allergic reactions have been very rarely reported with the administration of Infanrix. 10% of vaccinated people experienced the following side effects: redness/swelling/pain at the injection site, increased body temperature to low-grade levels.

Less frequently (in 0.1% of cases), complications such as lymphadenopathy, fever to febrile levels, compaction at the injection site, and severe restlessness of the child were recorded.

SPECIAL INSTRUCTIONS AND PRECAUTIONS FOR USE

Infanrix Hexa should under no circumstances be administered intravenously or intradermally.

Before vaccination, you should study the child’s medical history, paying attention to previous administration of vaccines and the associated occurrence of adverse reactions, and also conduct an examination. As with any other vaccine, you should have everything you need ready to stop a possible anaphylactic reaction to Infanrix Hexa. The vaccinated person must be under medical supervision for 30 minutes after immunization. The occurrence of the following reactions after administration of the Infanrix Hexa vaccine is not a contraindication for subsequent vaccinations, however, the benefit-risk ratio must be taken into account:

• Temperature 40 C, occurring within 48 hours;
• Collapse or shock-like state that developed within 48 hours after administration of the vaccine;
• A high-pitched scream lasting 3 hours or more, occurring within 48 hours after vaccine administration;
• Febrile or afebrile seizures that occurred within 3 days after vaccination.

Infanrix Hexa should be used with caution in patients with thrombocytopenia or coagulation disorders, as intramuscular injection may cause bleeding in such patients.

As with any other vaccination, not all vaccinated individuals may exhibit a protective immune response.

Infanrix Hexa does not prevent the development of diseases caused by any other pathogens, with the exception of Corynebacterium diphthenae, Clostridium lelani, Bordetellopertussis, hepatitis B virus, polio virus types 1,2,3 and Haemophilus influenzae type b. However, a preventive effect is expected against hepatitis D. which can be prevented by vaccination, because hepatitis D (caused by hepatitis delta virus) does not occur in the absence of hepatitis B virus.

There is limited evidence based on vaccination of 169 preterm infants to suggest that Infanrix Hexa can be administered to preterm infants. However, they may have a lower immune response

HIV infection is not a contraindication to vaccination. However, after vaccination in immunocompromised patients, the expected immunological response may also not be achieved. Since Haemophilus influenzae b capsular polysaccharide antigen is excreted in the urine, a positive test may be recorded in a urine test within 1-2 weeks after vaccination. During this period, other tests are necessary to confirm the diagnosis of infection caused by Haemophilus influenzae type b.

In children with progressive neurological disorders, including infantile spasms, uncontrolled epilepsy, or progressive encephalopathy, pertussis vaccination (both whole cell and acellular vaccines) should be delayed until the condition is stabilized. The decision to prescribe a vaccine containing pertussis should be made individually after a careful assessment of the benefits and risks.

It is necessary to take into account the potential risk of apnea and the need to monitor respiratory function for 72 hours during primary vaccination of children born prematurely (from 28 weeks of gestation) and. especially children with respiratory distress syndrome. Due to the need to vaccinate children in this group, primary vaccination should not be delayed or denied. The primary course of vaccination for such children should be carried out in a hospital setting under the supervision of a doctor for 72 hours. After vaccination or sometimes before it, fainting or severe weakness is possible as a psychological reaction to the injection. Before vaccination, it is important to make sure that the patient will not be harmed in case of fainting.

A history of febrile seizures, a family history of seizures, or sudden infant death syndrome is not a contraindication, but requires special attention. Such vaccinated people should be observed for 2-3 days, since during this period an undesirable event may occur.

How is vaccination carried out?

Vaccination is carried out in a vaccination room, in compliance with all sanitary requirements. All drugs are certified. A certificate for the drug is provided upon request.

Without reminders, before vaccination, the medical worker must show the drug and the expiration date of the vaccine.

Only sterile and disposable instruments are used. The vaccination must be carried out using disposable medical gloves.

On the day of vaccination, the child is examined by a pediatrician and the temperature is measured. In the absence of contraindications, vaccination is carried out. Information about the vaccination performed is entered into the card, vaccination certificate, and detailed recommendations for caring for the child in the post-vaccination period are given.

Before vaccination, the doctor will answer all your questions. Be sure to bring information about previous vaccinations to your appointment!

Please note that vaccination of a child, Mantoux test, Diaskintest can only be carried out in the presence of parents or legal representatives of the child (guardians), or if the accompanying person has a NOTARIZED power of attorney to carry out the manipulation (indicating the drug planned for administration) . Otherwise, vaccination will be denied. We comply with the laws of the Russian Federation.

Only here!

When should the Infanrix Hexa vaccine not be given?

- if the test results do not comply with the standards

- at elevated temperature in a child

- in case of intolerance to the components contained in the Infarnrix Hexa vaccine

- during exacerbation of chronic diseases

- in other cases mentioned by the pediatrician before vaccination

Additional Information

Is it possible to purchase Infanrix Hexa from us or where to buy Infanrix Hexa in Moscow?

Family Medical does not sell the Infanrix Hexa vaccine, we vaccinate.

Where to get vaccinated with Infanrix Hexa in Moscow?

You can vaccinate with Infanrix Hexa in medical and “Our Children”, the Infanrix Hexa vaccine is available. Vaccination requires a mandatory examination before vaccination, the vaccination itself and observation after vaccination.

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