Imported DTP vaccine: names, review of drugs, which is better to choose

To prevent negative consequences after vaccination, most parents prefer the imported DTP vaccine.

This abbreviation stands for adsorbed pertussis-diphtheria-tetanus vaccine. To a greater extent, this choice is based on distrust of domestically produced drugs. But, before you understand which is better, it is necessary to consider the positive and negative aspects of not only foreign analogues, but also their Russian representatives.

Advantages of imported DTP

Manufacturers offer a wide variety of DTP vaccinations, each of which has a significant difference compared to Russian ones.

First of all, it is worth noting that the imported analogues do not contain components such as merthiolate and formaldehyde, which are prohibited for use in the production of drugs in the European Union, as well as in the United States of America. In addition, cell-free technology is used to manufacture the anti-whooping cough component in imported drugs.

The main feature of this composition, which does not contain harmful preservatives, is to minimize the risks developing in a child after vaccination.

Among the most common complications that can be dangerous for children are:

increased body temperature;
allergic rashes;
swelling;
convulsions.

Foreign substitutes for DPT also contain additional components, which makes it possible to reduce the severity of the immune reaction of the human body, unlike domestic vaccines.

The form of release of foreign drugs also plays an equally important role. Disposable dosage kits are much more convenient to use and store. They must be stored in a dark place, protected from moisture. The optimal temperature is 2-8 degrees Celsius.

It is important to remember that such preparations should not be frozen.

Is it possible to get a foreign vaccination after the domestic one?

Some parents are interested in whether it is possible to revaccinate with a foreign drug after DTP.
The need to replace the vaccine arises for various reasons. For example, a child experienced severe side effects and complications after the first injection. It should be noted that if DPT is poorly tolerated, then it is better not to use the medication: with each subsequent injection the reaction will be more pronounced.

Many parents, having read positive reviews about foreign vaccinations, want to replace the domestic drug, but no one can guarantee that such analogues will be well tolerated. Negative post-vaccination symptoms are also observed among foreign vaccinations.

Doctors allow the use of imported vaccines after DTP . Pediatricians note that immunization against tetanus, whooping cough and diphtheria with various drugs does not distort the result, but promotes the high-quality production of antibodies.

But doctors warn that when replacing a domestic vaccine with a foreign one, it is necessary to take into account the type of drug and the schedule for the prevention of infectious and viral diseases: many imported analogues of DPT protect simultaneously not from three, but from four or five pathologies.

Name of drugs

Foreign pharmacological companies offer several types of drugs.

Infanrix

Despite the fact that the procedure is paid, vaccination with this drug is now widespread in Russian clinics. The vaccine is produced in the UK by GlaxoSmithKline.

In addition to the fact that it contains pertussis microbes, it contains toxoids, which make it easier to tolerate the vaccination.

Among the main disadvantages, there is insufficiently high efficiency, which is explained by providing only 88% protection for the child from infection.

Produced in ampoules in the form of a suspension. The vaccine is given via intramuscular injection.

Infanrix Hexa

Since a child is exposed to many injections over a short period of time, foreign manufacturers have begun to combine most vaccinations into one vaccine, called Infanrix Hexa.

This drug helps prevent the development of:

whooping cough;
tetanus;
polio;
hepatitis B;
diphtheria;
hemophilus influenzae infection.

Most often used when the hepatitis and DTP vaccination schedules coincide.

Infanrix Penta

This suspension is a continuation of the Infanrix IPV vaccine. It is distinguished by the presence of an additional component. It has a standard vaccination and revaccination schedule.

D. T. KOK

The vaccine is also adsorbed. It is produced in France. Helps protect against diseases such as tetanus, whooping cough and diphtheria.

The suspension can be used together with others. This is due to the absence of risks associated with children's health or the effectiveness of vaccination. Vaccination is carried out 3 times.

The minimum time interval after which vaccinations are given is 1 month. Revaccination is carried out 12 months after the first course of vaccinations.

Tetraxim

Also produced by French manufacturers. The drug is complex. It contains substances that help prevent diphtheria, whooping cough and tetanus.

It also contains an additional component that provides protection against polio, which allows you to replace two injections with one.

Cell-free technology is used for production. Due to the absence of formalin and merthiolate, the vaccine is considered one of the safest and of higher quality.

Tetrakok 05

Just like after domestic drugs, in this case it is rare, but the development of side effects is not excluded, which include:

pain at the injection site;
temperature rise to 38.5 degrees Celsius and above;
allergies, which manifests itself in the form of rash, hives and itching;
anaphylactic shock (in rare cases).

If any of these complications occur, it is recommended to seek advice from a specialist. If an allergic reaction occurs, then another drug must be used in the future.

Pentaxim

When using a vaccine called Pentaxim, a pronounced reaction of the body is diagnosed in exceptional cases. The components included in the drug help develop immunity to diseases.

Belgian DPT vaccine

Made here https://www.loc10.ru/

Injected with Infanrix and Imovax (poliomelitis)

Signing up was easy. At 12.00. Not morning, not day, I liked this time.

We went by car. I don’t know how to do it on my own.

Polite. Soulful people.

The therapist, a supporter of homeopathy, talked about the harms and benefits of vaccinations, advised and prescribed some useful homeopathic remedies.

A very careful and complete inspection.

Pentaxim 2 thousand odd (2,200 or so) purely for the vaccine - it was unexpectedly expensive for us - we didn’t take any money with us.

They only injected Imovax from under the counter. It was not available - now they don’t allow commercial people to buy it - only on state holidays - the doctor gave “her” vaccine.

They gave the vaccine boxes to make sure that they were cool, that the expiration date had not expired, and that the packaging was not damaged.

The nurse pierced it so much that the baby doll didn’t notice anything at all and continued to play the bell for himself. They stabbed me in the ass and thigh.

Infanrix - 1300 rub. This is the cost of the vaccine + examination by a therapist

+ cheated *didn’t talk about it on the phone* for 150 rubles for an injection *nursing*

Imovax - 600 rub.

Everything is fine.

It takes a long time to issue the payment. 30 minutes. Well, it doesn’t matter - you still sit for 30-40 minutes waiting for anaphylactic shock.

From my personal paddocks:

Next time I will look more closely at where the nurse went and what she sucked into the syringe. I always imagine that they show you a drug in your mouth, and then quietly walk away and draw something else into a syringe * and then they will sell your vaccine * - well, these are my personal timid cockroaches.))

UPD

Even when I was pregnant, I almost went crazy thinking about whether to vaccinate or not.

These neo-agitations on the Internet against vaccinations were confusing, and the hundred-year-old practicing pediatricians were also confusing, screaming that they had gone crazy with their Internet and there was an infection all around... The head wanted to point to the west. I corresponded with people living in Switzerland (a couple of years ago I wanted to go there and live there for good) - people wrote that they don’t get any vaccinations until they are a year old, only one of a kind, and that’s optional.

In the end, I decided that if we lived in Europe or in Switzerland, where they would never allow a wild Tajik with a trunk, I would not get vaccinated. After all, they really leave their imprint on the body. In the brain, on the immune system, on the psyche. And there are also complications (!!!) ..... but living in Russia where no one washes the sidewalk with shampoo, in Moscow where wild Tajiks rush around in crowds with their trunks and the subway with a closed air exchange - I decided that the risk of contracting such hellish infections is much higher -much greater than the risk of complications after vaccination.

Vaccinations are risky. Driving a car is a risk - you can get into an accident. Giving food to a child is a risk - there may be choking, there may be an allergy. There are many risks in our life. I decided to approach this as wisely and carefully as possible.

And most importantly, choose quality vaccines wisely.

Not DTP in a shitty clinic with a shitty nurse, but the most purified and gentle Belgian vaccine Infanrix.

And Imovax as an injection against polio.

Next, I will get some non-threatening vaccinations at the clinic. And those that are more serious are in qualified centers.

I also prepared the child for vaccination.

Fenistil *Len, thank you for brainwashing me!* - I managed to apply it to the baby several times overnight (I doubted it at first, but in vain) - it is generally recommended 3 days before the vaccination and 3 after. Because the vaccine contains a ton of all sorts of chemical components besides the inoculating virus itself, the binding components - and there are allergies to them. And Fenistil removes and neutralizes.

Not injected on a full stomach. I brought them a slightly hungry child)

Calm atmosphere at home. Sufficient amount of fresh air.

Approximate cost difference

DTP drugs come in different price categories. In most cases, the cost will depend on the country producing the vaccine, as well as markups from pharmaceutical companies.

Suspension from foreign manufacturers is somewhat more expensive. In this regard, government medical institutions prefer to use domestic DTP vaccines. This is somewhat cheaper, but negative reactions in children are much more common.

However, in order to avoid or minimize the risk of side effects, it is possible to purchase the drug yourself.

So, for example, Pentaxim will cost about 1,400 rubles, the cost of Tetracoc varies between 860-1,300 rubles. Infanrix will cost approximately 1500-1800 rubles. The average price of the Russian drug Bubo-Kok is about 1,600 rubles.

Thus, we can say that the cost of imported vaccines is not much different from domestic ones if you purchase them yourself and then vaccinate your child at the clinic.

Names of analogues

Analogs of DPT can be purchased at paid medical centers (children are vaccinated here), as well as in large pharmacy chains.

Let's list the names of the vaccines:

Pentaxime, France . Contains components that form immunity against whooping cough, diphtheria, tetanus, polio and Haemophilus influenzae. The vaccine is approved for use from the age of 3 months. The standard regimen includes three primary vaccinations and one revaccination (one year after completion of the course). One of the most popular immunotherapy drugs in Russia, it has normal tolerability;
Tetracoque, France . This vaccination is four-component (whooping cough, diphtheria, tetanus, polio). The vaccine against Haemophilus influenzae or hepatitis B can be administered simultaneously, but this is two/three injections instead of one;
Infanrix, Belgium . The vaccine contains three components that protect against whooping cough, diphtheria and tetanus;
Infanrix Hexa, Belgium . There are six antigens, in addition to the three basic ones, components of hepatitis B, polio and Haemophilus influenzae are present. The presented vaccination is one of the most modern polyvaccines, causes minimal side effects, and has a high immune response. Suitable for use from two months;
Infanrix IPV . In addition to the three basic components, it also contains antigens to polio;
Bubo-Kok, Russia . Protects against diphtheria, tetanus, hepatitis B and whooping cough. Approved for use from three months. The vaccine is relatively new and is considered a safer analogue of DPT.

Vaccine Pentaxim
It is extremely important to understand in what cases the use of analogues is permissible and in what cases it is not. For example, if a child has been vaccinated with DTP, then it is possible to continue the course with Pentaxim, Infanrix or another immunodrug. If the baby was first vaccinated with foreign analogues, then “switching” from them to Russian is no longer recommended.

What to choose: imported drug or domestic

Before choosing a vaccine from a foreign or domestic manufacturer, you need to understand how they may differ.

When choosing a vaccine, it is important to consider parameters such as:

injection scheme;
compound;
reaction and possible side effects.

In the case where a child has a severe allergic reaction, it is better to give preference to foreign analogues. This is explained by the increased risk of developing a negative reaction to Russian DTP.

If we talk about the vaccination schedule, there are no differences. Vaccinations will be given according to the schedule presented by the National Vaccination Calendar.

Regardless of which drug is used, experts recommend preparing for vaccination in advance.

The list of preparatory activities includes:

the child takes an antihistamine for three days;
absence of colds, hyperemia, or any diseases.

Only a completely healthy child can be vaccinated, which will avoid possible negative consequences.

As for contraindications, there are no significant differences either..

Any company specializing in the production of DTP vaccines is maximally interested in the effectiveness of the drug and minimal risks for young patients. The main differences are only in price and possible manifestations of a negative reaction.

Each parent makes his own decision as to which vaccine to use: domestic or foreign.

According to statistics, even after using Pentaxim or Infanrix, there may be adverse reactions.

Which is better to vaccinate with DTP: imported or domestic?

Which is better to get the DTP vaccine, domestic or imported, each parent decides independently. Much depends on the financial situation, the health of the baby, the tolerability of individual components of the vaccine, and the availability of the required drug in the pharmacy.

A pediatrician can help with the choice. To make the right decision, it is worth considering the positive and negative aspects of foreign and Russian DTP.

Advantages of the domestic pertussis-diphtheria-tetanus vaccine:

no need to search for the drug in pharmacies. DPT is available in public health clinics and hospitals;
Vaccination is carried out free of charge within the established schedule.

Disadvantages of the Russian drug:

sometimes causes local and general adverse reactions;
in some cases it can provoke serious complications such as meningitis, encephalitis;
efficiency does not exceed 80-85%;
may not be well tolerated by weakened children and allergy sufferers.

Advantages of imported analogues of DTP:

are produced using a special technology that minimizes the load on the child’s body and reduces the likelihood of adverse reactions and complications;
do not contain whooping cough, Tween-80, or merthiolate in whole cells, which negatively affect the baby’s health;
form immunity to 4-5 viral and infectious pathologies at once. This allows you to reduce the number of injections, minimize the number of visits to the doctor, and reduce stress for the child;
protection efficiency is at least 95%;
have a more convenient release form. The injection solution is packaged in a syringe in a single dose. This makes the manipulation easier;
Suitable for immunization of weakened children and persons prone to allergic reactions and seizures.

Disadvantages of foreign vaccinations:

sometimes provokes adverse reactions of a local and general nature;
in some cases it can provoke serious complications;
the need to purchase the drug at the pharmacy;
the product is not always available at points of sale;
high cost of vaccination.

Vaccine Infanrix

If parents have enough financial resources, a foreign drug should be chosen for those children who are prone to allergic conditions and seizures. It is also better for weakened persons to inject Pentaxim or Infanrix instead of DPT.

Pediatricians note that allergies and other adverse reactions may also occur with Infanrix, Pentaxim, Tetracok and Tritanrix NV. Doctors advise choosing a drug based on the child’s health condition.

If the child does not have any special conditions or the budget does not allow purchasing an imported analogue, then vaccination can be performed with a domestic drug. In most children, this drug is well tolerated and does not cause any significant changes in well-being.

When is it better to refuse imported vaccines?

Vaccination is strictly contraindicated if:

hypersensitivity to the components included in the composition;
abnormalities in the nervous system;
hepatitis and tuberculosis;
impaired blood clotting;
acute pathologies of infectious and non-infectious origin.

Also contraindicated are the presence of high fever, nausea, vomiting and diarrhea.

DTP - what is it, risks and types of vaccines

Answering the first part of the question, you need to figure out what kind of vaccine it is. This Russian drug (DPT is the trade name) is designed to prevent three diseases - whooping cough, diphtheria and tetanus

. The components of diphtheria and tetanus rarely cause reactions in the body, but the pertussis component is different, it is the one that causes more reactions and is difficult to tolerate.

Whole cell and acellular vaccines

This particular vaccine is purchased in Krasnoyarsk clinics due to its low price. One dose costs the budget about one hundred rubles. DTP is a whole cell vaccine

, i.e. contain the entire cell of the whooping cough microbe, and this is a whole set of substances foreign to the human body. These substances in the DTP vaccine provoke a response from the body. And these reactions can be different, from mild ailments to extremely severe disorders. A slight increase in temperature, redness at the injection site, vomiting or diarrhea is considered common. Much more seriously, if a child begins to have convulsions, the temperature rises above 40 degrees. Particularly rare and extremely severe reactions are irreversible brain changes and even the death of the child. True, statisticians cite figures according to which unvaccinated children still die from whooping cough more often. But since this data does not reassure anyone, scientists around the world are struggling to create less dangerous vaccines, and they are succeeding.

acellular vaccines much easier

.
Although the listed complications and reactions, we emphasize, are also possible. Such vaccines are also purchased in our clinics, but in very small quantities, the city health department said, only for problem children (or those who are lucky - from the author). Such vaccines have fewer contraindications, less frequent temperature reactions, and most importantly, they exclude impurities, leaving only the main element of the microbe (protein), sufficient for the formation of immunity. Such vaccines are also called purified
. And they can be installed in Krasnoyarsk for money. To understand why it’s not free, just compare the price tag. This vaccine already costs 1000 rubles. It’s unaffordable for the budget, but parents can choose.

So, there are several vaccines available in private clinics in the city. By placing one of them, you will vaccinate your baby only against whooping cough, tetanus and diphtheria, the other also includes protection against other diseases. Let's see what's available in Krasnoyarsk.

"Infanrix"

Thus, the foreign drug "Infanrix"

contains only individual particles of the pertussis microorganism, plus it contains
diphtheria and tetanus toxoids
. This drug, of course, also has side effects and contraindications, although fewer than those of whole-cell vaccines.

"Pentaxim"

French vaccine "Pentaxim"

designed for broader prevention.
In addition to diphtheria, tetanus, whooping cough,
there are also components against
polio and Haemophilus influenzae infection
(meningitis, epiglottitis, pneumonia, septicemia, etc.).

This is how these two vaccines compare.

Infanrix is produced in Belgium (GlaxoSmithKline). Pentaxim is produced by Sanofi Pasteur, France. In the international rankings it is rated higher than, but both are quite high. In Pentax, the hemophilic component comes in a separate ampoule, so purely technically, it can be done or not.